Ultrasonic Homogenizer

An ultrasonic homogenizer is a laboratory instrument used to break down particles or cells in a liquid sample. It employs high-frequency sound waves to create cavitation, a process that involves the formation and collapse of microscopic bubbles in the liquid. This process generates intense localized pressures and temperatures, leading to cell disruption, particle size reduction, and improved mixing.

Key Applications:

• Cell Lysis: Disrupting cell membranes to release intracellular components.
• Emulsification: Creating stable emulsions of oil and water.
• Dispersion: Dispersing solid particles in liquid media.
• Homogenization: Creating uniform mixtures.
• Nanomaterial Synthesis: Synthesizing nanoparticles.

How it Works:

1. Ultrasonic Probe: A probe is immersed in the liquid sample.
2. High-Frequency Sound Waves: The probe emits high-frequency sound waves into the liquid.
3. Cavitation: The sound waves create microscopic bubbles that rapidly expand and collapse, generating intense localized energy.
4. Cell Disruption and Particle Size Reduction: The intense energy disrupts cell membranes and breaks down particles.

Key Features:

• Power Output: Determines the intensity of the ultrasonic waves.
• Frequency: The frequency of the sound waves affects the efficiency of the homogenization process.
• Probe Tip Design: Different probe tip designs are suitable for various applications.
• Temperature Control: Some homogenizers have temperature control to prevent sample overheating.

By using an ultrasonic homogenizer, researchers can efficiently prepare samples for various analytical techniques, such as spectroscopy, chromatography, and microscopy.